Epidural clonidine employed as an adjunct to local anesthetics has 3 different mechanisms of action. Initial, the stimulation of alpha-two-receptors within the dorsal horn minimizes pain transmission. Secondly, clonidine could potentially cause regional vasoconstriction that restrictions vascular elimination of regional epidural anesthetics. Clonidine treats substantial hypertension b... https://neilr468pjb4.digitollblog.com/profile