An Formal Site of The usa government. This is how you realize we are official. dot gov icon Nonabsorbed ursodiol passes to the colon wherever it is mostly seven-dehydroxylated to lithocholic acid. Some ursodiol is epimerized to chenodiol (CDCA) by means of a seven-oxo intermediate. Chenodiol also undergoes seven-dehydroxylation https://www.youtube.com/watch?v=A07qHOeWON8