If a affected person is simply too ill to have medical procedures and has serious ischemia (decreased oxygen during the tissues) that threatens the lack of a limb, angioplasty could also be attempted. Patients with critical limb ischemia/Continual limb-threatening ischemia (CLI/CLTI) at risk for establishing gangrene will current with limb discomfort https://sgvasculargrp.com/medical-condition/peripheral-arterial-disease/