If the pathogenic variant present in the proband can not be detected in the leukocyte DNA of either mother or father, the recurrence threat to sibs is approximated being one% based on the theoretic risk of parental germline mosaicism. If sequence Assessment of DGKE does not discover biallelic pathogenic variants, https://judahhhdwo.ka-blogs.com/85524279/facts-about-air-handling-unit-ahu-hire-revealed